دانلود مقاله ISI انگلیسی شماره 124968
ترجمه فارسی عنوان مقاله

رژیم های غذایی سرشار از موش های صحرایی ناسازگار جنبه های وظایف تصمیم گیری، انگیزه و حافظه فضایی است، اما تکانشی نیست که توسط عملگر تأخیر انجام شود

عنوان انگلیسی
High-sucrose diets in male rats disrupt aspects of decision making tasks, motivation and spatial memory, but not impulsivity measured by operant delay-discounting
کد مقاله سال انتشار تعداد صفحات مقاله انگلیسی
124968 2017 11 صفحه PDF
منبع

Publisher : Elsevier - Science Direct (الزویر - ساینس دایرکت)

Journal : Behavioural Brain Research, Volume 327, 1 June 2017, Pages 144-154

پیش نمایش مقاله
پیش نمایش مقاله  رژیم های غذایی سرشار از موش های صحرایی ناسازگار جنبه های وظایف تصمیم گیری، انگیزه و حافظه فضایی است، اما تکانشی نیست که توسط عملگر تأخیر انجام شود

چکیده انگلیسی

Excessive consumption of sugar sweetened drinks is proposed to produce functional changes in the hippocampus and prefrontal cortex, leading to perturbations in behavioural control. Impairments in behavioural control have been observed in obese people on tasks that involve making choices, including delay-discounting, indicative of increased impulsivity. In this study we examined the impact of 2 h daily access to 10% sucrose (or no sucrose in controls) in young male rats on behavioural tasks reliant on hippocampal function including delay-discounting, T-maze forced choice alternation and place recognition memory, as well as progressive ratio to measure motivation. We observed deficits in place recognition memory and T-maze forced choice alternation, indicative of hippocampal deficits in rats with a history of sucrose consumption. Moreover, rats with a history of sucrose consumption were less motivated to lever press for rewards on a progressive ratio schedule. However, rats with a history of sucrose consumption performed equally to control animals during the delay-discounting task, suggesting that they discounted for reward size over a delay in a manner comparable to control animals. These findings indicate that high-sucrose diets impact on spatial and working memory processes, but do not induce impulsive-like choice behaviours in rats, suggesting that unhealthy diet choices may not influence this aspect of decision-making behaviour.