لیپیدوم در اختلال افسردگی عمده: تاثیر ژنتیکی مشترک برای اتر فسفاتیدیلولین، فنوتیپ مبتنی بر پلاسما مربوط به التهاب و خطر بیماری

This study is the first to demonstrate a shared genetic etiology between MDD and ether-phosphatidylcholine species containing arachidonic acid, an omega-6 fatty acid that is a precursor to inflammatory mediators, such as prostaglandins. The study highlights the potential utility of the well-characterized linoleic/arachidonic acid inflammation pathway as a diagnostic marker and/or treatment target for MDD.