ترکیبات نیمه متمایز عوامل خطرساز روانشناختی، متابولیکی و التهابی، به طور پیوسته با شروع انواع زیرمجموعه اختلال افسردگی عمده در میانسالی

Our data suggest that MDD subtypes are predicted by partially distinct combinations of baseline characteristics suggesting that these subtypes not only differ in their clinical manifestations but also in factors that contribute to their development. Subjects with minor depressive episodes, especially in combination with particular personality features, deserve close clinical attention to prevent the subsequent onset of atypical and melancholic major depression.