دانلود مقاله ISI انگلیسی شماره 73511
ترجمه فارسی عنوان مقاله

ناهنجاری های جسمی جزئی در زنان مبتلا به افسردگی تک قطبی مکرر

عنوان انگلیسی
Minor physical anomalies in women with recurrent unipolar depression
کد مقاله سال انتشار تعداد صفحات مقاله انگلیسی
73511 2010 4 صفحه PDF
منبع

Publisher : Elsevier - Science Direct (الزویر - ساینس دایرکت)

Journal : Psychiatry Research, Volume 176, Issue 1, 30 March 2010, Pages 22–25

ترجمه کلمات کلیدی
ناهنجاری های جسمی جزئی؛ افسردگی؛ روان پریشی؛ عصبی
کلمات کلیدی انگلیسی
Minor physical anomalies; Depression; Psychosis; Neurodevelopment

چکیده انگلیسی

According to earlier observations, minor physical anomalies (MPAs) are more prevalent in psychotic disorders, especially in schizophrenia, and represent an indicator of abnormal fetal development. Limited research has been conducted on these structural abnormalities among patients with unipolar depression, with and without psychotic features. We hypothesized that the mean total MPA score would be greater in patients with psychotic depression than depressive patients without psychosis and control subjects. An extended scale of MPAs was used to detect the presence or absence of 51 MPAs in women with recurrent unipolar depression with psychotic symptoms (n = 50), women with recurrent unipolar depression without psychotic symptoms (n = 50) and healthy female controls (n = 50). Women with recurrent depression had significantly more MPAs than controls. With regard to MPAs of specific body regions, depressive patients had significantly higher rates of MPAs in the mouth area than control subjects. Higher rates of MPAs were not significantly related to psychotic features of depression. The study results are indicative of possible early neurodevelopmental disturbance in recurrent unipolar depression.