بلوک سنتز گلوکوکورتیکوئید در هنگام فعال کردن مجدد ممکن است منقطع از یک حافظه ترس موجود باشد

We demonstrate that extinction of a classical contextual fear memory is dependent on endogenous glucocorticoid synthesis during re-activation of a fear memory. Our data suggest that decreased glucocorticoids during fear memory re-activation may contribute to the inability to extinguish a fear memory, thus contributing to one of the core symptoms of PTSD.