مهار پیش گزیده ای از رفلکس بی نظمی در اسکیزوفرنیا با استفاده از یک پارادایم متقابل

To the best of our knowledge, this is the first study showing reduced PPI in patients with schizophrenia by using an electrocutaneous-acoustic prepulse-pulse combination. Hence, this study gives further evidence of a modality-independent sensorimotor gating deficit in schizophrenia. Furthermore, as PPI was also lower than usual in controls using unimodal paradigms, results are interpreted in favour of longer processing times of the electrocutaneous prepulse, which probably led to a shorter perceived stimulus onset asynchrony (SOA) in the brain.