شواهد عصبی برای کنترل ضعف بالا به پایین پردازش تصویر در بیماری پارکینسون و آلزایمر

Impaired recognition of objects presented in unconventional orientations in MCI due to PD and AD was associated with decreased activation of frontoparietal regions, consistent with defective top-down regulation of visual processing. Aberrant activation of superior parietal cortex may serve as an early imaging biomarker of impending cognitive impairment in PD.