در اثر انقراض موجب ترس و وحشت می شود با میکروارگانیسم ماده سفید و اتصال به عملکرد مرتبط است

These data indicate that structural integrity of the cingulum is directly associated with extinction learning and appears to influence functional connectivity between these regions. Decrements in cingulum microstructure may interfere with extinction learning, thereby increasing risk for the development of pathological anxiety.