Our study showed that psychiatric symptomatology and childhood traumatic experiences were considerably higher in mothers of children with PNE. This study highlights the importance of evaluating PNE not only from a biological aspect, but also in terms of psychosocial factors, including assessment of the mother's mental status.Table. Major psychiatric and sociodemographic differences found between mothers of children with primary nocturnal enuresis and mothers of non-enuretic controls.MoPNEMoNECp-valueaAge, median (25th, 75th)35 (27, 39)34 (31, 37)0.502Number of children, median (25th, 75th)3 (2, 4)2 (2, 2.5)<0.001Number of mothers with enuresis history in childhood12 (26,7%)3 (6, 7%)0.011MoPNE median (25th, 75th)MoNEC, median (25th, 75th)Sexual abuse (CTQ)5 (5, 5)5 (5, 7)0.041Physical neglect (CTQ)7 (6, 11.75)6 (5, 8)0.001Extraversion (EPQR-A)4 (2, 5)5 (2.5, 6)0.049Lying (L) (EPQR-A)5 (4, 6)5 (4, 6)0.019General psychopathology index (SCL 90-R)0.9 (0.46, 1.56)0.41 (0.21, 0.67)<0.001MoPNE, mother of children with primary enuresis nocturna; MoNEC, mother of non-enuretic children; CTQ, Childhood Trauma Questionnaire; EPQR-A, Eysenck Personality Questionnaire Revised Abbreviated; SCL-90-R, Symptom Checklist-90.aMannâWhitney U test.