آماده سازی و مشخص کردن نانوذرات هیدروکسی آپاتیت که انسولین و اسید گالیک را برای تحویل دهان انسولین نگهداری می کنند

A safe, non-toxic, and effective oral insulin delivery system based on hydroxyapatite (HAP) nanoparticles functionalized by polyethylene glycol (PEG) that decrease blood glucose level of T1D rats was successfully developed. It can help gallic acid and insulin successfully escape from the enzymes in the gastrointestinal (GI) tract, and deliver insulin into the systematic circulation with the insulin signaling pathway eventually being activated. (403KB)