دانلود مقاله ISI انگلیسی شماره 71982
ترجمه فارسی عنوان مقاله

اثرات مربوط به سن بر روی ارتباطات عصبی بازیابی حافظه شرح حال

عنوان انگلیسی
Age-related effects on the neural correlates of autobiographical memory retrieval
کد مقاله سال انتشار تعداد صفحات مقاله انگلیسی
71982 2012 13 صفحه PDF
منبع

Publisher : Elsevier - Science Direct (الزویر - ساینس دایرکت)

Journal : Neurobiology of Aging, Volume 33, Issue 7, July 2012, Pages 1298–1310

ترجمه کلمات کلیدی
پیری - fMRI؛ حافظه شرح حال؛ هیپوکامپ؛ قشر جلوی مغز؛ حافظه اپیزودیک؛ اتصال موثر
کلمات کلیدی انگلیسی
Aging; fMRI; Autobiographical memory; Hippocampus; Prefrontal cortex; Episodic memory retrieval; Effective connectivity
پیش نمایش مقاله
پیش نمایش مقاله  اثرات مربوط به سن بر روی ارتباطات عصبی بازیابی حافظه شرح حال

چکیده انگلیسی

Older adults recall less episodically rich autobiographical memories (AM), however, the neural basis of this effect is not clear. Using functional MRI, we examined the effects of age during search and elaboration phases of AM retrieval. Our results suggest that the age-related attenuation in the episodic richness of AMs is associated with difficulty in the strategic retrieval processes underlying recovery of information during elaboration. First, age effects on AM activity were more pronounced during elaboration than search, with older adults showing less sustained recruitment of the hippocampus and ventrolateral prefrontal cortex (VLPFC) for less episodically rich AMs. Second, there was an age-related reduction in the modulation of top-down coupling of the VLPFC on the hippocampus for episodically rich AMs. In sum, the present study shows that changes in the sustained response and coupling of the hippocampus and prefrontal cortex (PFC) underlie age-related reductions in episodic richness of the personal past.