دانلود مقاله ISI انگلیسی شماره 75307
ترجمه فارسی عنوان مقاله

درد نوزادان، تعامل و استرس والدگری در رابطه با رشد شناختی و حرکتی در 8 و 18 ماهگی در نوزادان نارس

عنوان انگلیسی
Neonatal pain, parenting stress and interaction, in relation to cognitive and motor development at 8 and 18 months in preterm infants
کد مقاله سال انتشار تعداد صفحات مقاله انگلیسی
75307 2009 9 صفحه PDF
منبع

Publisher : Elsevier - Science Direct (الزویر - ساینس دایرکت)

Journal : Pain, Volume 143, Issues 1–2, May 2009, Pages 138–146

ترجمه کلمات کلیدی
درد، نوزادان نارس؛ نوزادان؛ فشار؛ عصبی؛ والدین
کلمات کلیدی انگلیسی
Pain; Premature infants; Neonatal; Stress; Neurodevelopment; Parent
پیش نمایش مقاله
پیش نمایش مقاله  درد نوزادان، تعامل و استرس والدگری در رابطه با رشد شناختی و حرکتی در 8 و 18 ماهگی در نوزادان نارس

چکیده انگلیسی

Procedural pain in the neonatal intensive care unit triggers a cascade of physiological, behavioral and hormonal disruptions which may contribute to altered neurodevelopment in infants born very preterm, who undergo prolonged hospitalization at a time of physiological immaturity and rapid brain development. The aim of this study was to examine relationships between cumulative procedural pain (number of skin-breaking procedures from birth to term, adjusted for early illness severity and overall intravenous morphine exposure), and later cognitive, motor abilities and behavior in very preterm infants at 8 and 18 months corrected chronological age (CCA), and further, to evaluate the extent to which parenting factors modulate these relationships over time. Participants were N = 211 infants (n = 137 born preterm ⩽32 weeks gestational age [GA] and n = 74 full-term controls) followed prospectively since birth. Infants with significant neonatal brain injury (periventricular leucomalacia, grade 3 or 4 intraventricular hemorrhage) and/or major sensori-neural impairments, were excluded. Poorer cognition and motor function were associated with higher number of skin-breaking procedures, independent of early illness severity, overall intravenous morphine, and exposure to postnatal steroids. The number of skin-breaking procedures as a marker of neonatal pain was closely related to days on mechanical ventilation. In general, greater overall exposure to intravenous morphine was associated with poorer motor development at 8 months, but not at 18 months CCA, however, specific protocols for morphine administration were not evaluated. Lower parenting stress modulated effects of neonatal pain, only on cognitive outcome at 18 months.