دانلود مقاله ISI انگلیسی شماره 119438
ترجمه فارسی عنوان مقاله

همبستگی عصبی خاطرات دوام در طول عمر بالغ: فعالیت مغز در رمزگذاری و بازیابی

عنوان انگلیسی
Neural correlates of durable memories across the adult lifespan: brain activity at encoding and retrieval
کد مقاله سال انتشار تعداد صفحات مقاله انگلیسی
119438 2017 74 صفحه PDF
منبع

Publisher : Elsevier - Science Direct (الزویر - ساینس دایرکت)

Journal : Neurobiology of Aging, Volume 60, December 2017, Pages 20-33

پیش نمایش مقاله
پیش نمایش مقاله  همبستگی عصبی خاطرات دوام در طول عمر بالغ: فعالیت مغز در رمزگذاری و بازیابی

چکیده انگلیسی

Age-related effects on brain activity during encoding and retrieval of episodic memories are well documented. However, research typically tests memory only once, shortly after encoding. Retaining information over extended periods is critical, and there are reasons to expect age-related effects on the neural correlates of durable memories. Here, we tested whether age was associated with the activity elicited by durable memories. One hundred forty-three participants (22–78 years) underwent an episodic memory experiment where item-context relationships were encoded and tested twice. Participants were scanned during encoding and the first test. Memories retained after 90 minutes but later forgotten were classified as transient, whereas memories retained after 5 weeks were classified as durable. Durable memories were associated with greater encoding activity in inferior lateral parietal and posteromedial regions and greater retrieval activity in frontal and insular regions. Older adults exhibited lower posteromedial activity during encoding and higher frontal activity during retrieval, possibly reflecting greater involvement of control processes. This demonstrates that long-lasting memories are supported by specific patterns of cortical activity that are related to age.