دانلود مقاله ISI انگلیسی شماره 119447
ترجمه فارسی عنوان مقاله

الگوهای مشابهی از عملکرد عصبی عملکرد حافظه را در طی رمزگذاری و بازیابی پیش بینی می کنند

عنوان انگلیسی
Similar patterns of neural activity predict memory function during encoding and retrieval
کد مقاله سال انتشار تعداد صفحات مقاله انگلیسی
119447 2017 36 صفحه PDF
منبع

Publisher : Elsevier - Science Direct (الزویر - ساینس دایرکت)

Journal : NeuroImage, Volume 155, 15 July 2017, Pages 60-71

پیش نمایش مقاله
پیش نمایش مقاله  الگوهای مشابهی از عملکرد عصبی عملکرد حافظه را در طی رمزگذاری و بازیابی پیش بینی می کنند

چکیده انگلیسی

Neural networks that span the medial temporal lobe (MTL), prefrontal cortex, and posterior cortical regions are essential to episodic memory function in humans. Encoding and retrieval are supported by the engagement of both distinct neural pathways across the cortex and common structures within the medial temporal lobes. However, the degree to which memory performance can be determined by neural processing that is common to encoding and retrieval remains to be determined. To identify neural signatures of successful memory function, we administered a delayed free-recall task to 187 neurosurgical patients implanted with subdural or intraparenchymal depth electrodes. We developed multivariate classifiers to identify patterns of spectral power across the brain that independently predicted successful episodic encoding and retrieval. During encoding and retrieval, patterns of increased high frequency activity in prefrontal, MTL, and inferior parietal cortices, accompanied by widespread decreases in low frequency power across the brain predicted successful memory function. Using a cross-decoding approach, we demonstrate the ability to predict memory function across distinct phases of the free-recall task. Furthermore, we demonstrate that classifiers that combine information from both encoding and retrieval states can outperform task-independent models. These findings suggest that the engagement of a core memory network during either encoding or retrieval shapes the ability to remember the past, despite distinct neural interactions that facilitate encoding and retrieval.