اثر غلظت کلسترول بر خواص دو لایه و شکل گیری فاز دو لایه نئوماس: یک مطالعه شبیه سازی دینامیک مولکولی

Molecular dynamics simulations were carried out to investigate structural and dynamical properties of niosome bilayers with difference cholesterol concentrations (0–70 mol% Chol). Addition of cholesterols in the niosome bilayer significantly changes the molecular structure and stability. Increasing of cholesterol concentrations causes the area per molecule to increase and bilayer thickness decrease, suggesting that the niosome bilayer is expanded from the gel to the liquid ordered phase. (53KB)