واکنش پذیری پاداش آمیگدال، پیوند میان پاسخ استرس پیش دبستانی و شدت افسردگی را متمایز می کند

Results suggest that altered neural processing of reward is already related to increased cortisol output and depression severity in preschoolers. These results also demonstrate an important role for amygdala function as a mediator of this relationship at a very early age. Our results further underscore early childhood as an important developmental period for understanding the neurobiological correlates of early stress and increased risk for depression.