استفاده طولانی مدت از درمان ضد ترومبوی دوگانه برای پیشگیری ثانویه از وقایع آترترومبوتیک: متاآنالیز آزمایشهای تصادفی کنترل شده

Long-term use of DAPT for secondary prevention is associated with lower risk of death, MI and stroke beneficial especially in patients with prior MI and stroke, but it is associated with increased risk of bleeding. Prolonging DAPT requires careful assessment of the trade-off between ischemic and bleeding complications and should probably be reserved for patients with higher risk for atherothrombotic events.