تنوع در افراد مسن با کاهش تولید کورتیزول همراه است

This study is the first to investigate the association between the HPA–axis and loneliness in a large group of older adults aged 60–93 years. We found lower cortisol output in the first hour after awakening and lower dexamethasone suppression ratio in lonely older depressed and non–depressed adults. Whether diminished cortisol output is the underlying mechanism that leads to health problems in lonely older adults is an interesting object for further study.