دانلود مقاله ISI انگلیسی شماره 134092
ترجمه فارسی عنوان مقاله

تأثیر قدرت محرک بر میزان رقابت دوقطبی در افراد سالم: نتایج تحقیق در مورد تفاوتهای ژنتیکی، بالینی و فردی

عنوان انگلیسی
The effect of stimulus strength on binocular rivalry rate in healthy individuals: Implications for genetic, clinical and individual differences studies
کد مقاله سال انتشار تعداد صفحات مقاله انگلیسی
134092 2017 10 صفحه PDF
منبع

Publisher : Elsevier - Science Direct (الزویر - ساینس دایرکت)

Journal : Physiology & Behavior, Volume 181, 1 November 2017, Pages 127-136

ترجمه کلمات کلیدی
اندوفنوتایپ نرخ رقابت دوقلو، ادراک های مختلف قدرت تحریک کننده سرعت رانش سایز دیافراگم، تفاوتهای فردی، سطح
کلمات کلیدی انگلیسی
Binocular rivalry rate endophenotype; Mixed percepts; Stimulus strength; Drift speed; Aperture size; Individual differences; Levelt;
پیش نمایش مقاله
پیش نمایش مقاله  تأثیر قدرت محرک بر میزان رقابت دوقطبی در افراد سالم: نتایج تحقیق در مورد تفاوتهای ژنتیکی، بالینی و فردی

چکیده انگلیسی

Binocular rivalry (BR) occurs when conflicting images concurrently presented to corresponding retinal locations of each eye stochastically alternate in perception. Anomalies of BR rate have been examined in a range of clinical psychiatric conditions. In particular, slow BR rate has been proposed as an endophenotype for bipolar disorder (BD) to improve power in large-scale genome-wide association studies. Examining the validity of BR rate as a BD endophenotype however requires large-scale datasets (n = 1000 s to 10,000 s), a standardized testing protocol, and optimization of stimulus parameters to maximize separation between BD and healthy groups. Such requirements are indeed relevant to all clinical psychiatric BR studies. Here we address the issue of stimulus optimization by examining the effect of stimulus parameter variation on BR rate and mixed-percept duration (MPD) in healthy individuals. We aimed to identify the stimulus parameters that induced the fastest BR rates with the least MPD. Employing a repeated-measures within-subjects design, 40 healthy adults completed four BR tasks using orthogonally drifting grating stimuli that varied in drift speed and aperture size. Pairwise comparisons were performed to determine modulation of BR rate and MPD by these stimulus parameters, and individual variation of such modulation was also assessed. From amongst the stimulus parameters examined, we found that 8 cycles/s drift speed in a 1.5° aperture induced the fastest BR rate without increasing MPD, but that BR rate with this stimulus configuration was not substantially different to BR rate with stimulus parameters we have used in previous studies (i.e., 4 cycles/s drift speed in a 1.5° aperture). In addition to contributing to stimulus optimization issues, the findings have implications for Levelt's Proposition IV of binocular rivalry dynamics and individual differences in such dynamics.