فینگولیمود در اسکلروز متعدد عود بیماری: تجزیه و تحلیل یکپارچه از یافته های ایمنی

AV, atrioventricular; FREEDOMS, FTY720 Research Evaluating Effects of Daily Oral Therapy in Multiple Sclerosis; HPS, haemophagocytic syndrome; LRTI, lower respiratory tract infection; MS, multiple sclerosis; PML, progressive multifocal leukoencephalopathy; PRES, posterior reversible encephalopathy syndrome; S1PR, sphingosine 1-phosphate receptor; TRANSFORMS, Trial Assessing Injectable Interferon Versus FTY720 Oral in Relapsing–Remitting Multiple Sclerosis; ULN, upper limit of normalFingolimod; Multiple sclerosis; Safety; Adverse events; Cardiovascular events; Pooled analysis